Resistive economy is a term refers to circumvent the sanctions against a country or region experiencing sanctions. Generally, resistive economy means replacing local inputs for imported inputs and an increase in barter trade, but in Iran’s economy it has more extensive dimensions. The term resistive economy is declared by Iran’s supreme leader ayatollah Khamenei in august 2012 to overcome the barriers in economic development. The aim of the current study is to investigate this proposed economic model and its various dimensions and also its implementation in Islamic republic of Iran. The method of research is empirical which tests the feasibility of solution using empirical evidences based on the statistical applications. The results of the study show implementation of resistive economy despite of remarkable achievements in oil, gas and petrochemicals failed in other various segments. Additionally, mismanagement in distribution of foreign currencies is another issue in implementation of resistive economy in Iran.