Considering the importance of resistance economy as a strategic policy announced by the Supreme Leader in Iran and Islamic societies and the interpretation of this strategy in the Islamic economic system, this study aims to investigate the components of resistance economy and their impact on variables. Macroeconomic from the point of view of Imam Ali (AS) has been done using the causal method. In the component of fundamental justice, the fair distribution of income through the channel of increasing the demand of the average person in society affects the variables, employment, savings, investment and accelerating economic growth. In the knowledge-based component of economics, the application of knowledge and information can have a positive effect on the optimal use of resources, reduce production costs, increase income, savings, investment and economic growth by increasing productivity. Focusing on the domestic production sector in the form of the endogenous component of the economy, causes self-sufficiency and saves society from dependence. In the extraversion component, increasing the export of a reasonable plan to deal with the balance of payments deficit, optimal use of existing and potential facilities, providing a comparative advantage in the production of export goods, productivity of production factors, improving competition between producers, strengthening quality Products, foreign exchange, attracting foreign investment, expanding the domestic market, the possibility of using high levels of updated technology, economic growth and ultimately exports can bring a share of foreign trade and international markets. The variable of privatization leads to economic growth through microeconomics and macroeconomic variables channels